If you knew you had a 50/50 chance of inheriting a genetic disease, would you want to know? What Comes Next by Caitlin Forbes is an emotional roller coaster that makes you want to hug your sister, pet your dog, and wonder if it’s better to hide from the truth or not.

4/5 stars ★★★★☆
From the publisher: An empowering and heartfelt novel about the complexities of family, the power of sisterhood, and the bravery it takes to choose happiness when all seems lost.
Published on: October 14, 2025
Pages: 317
Genres: Women’s Fiction, Contemporary Romance, Drama, Coming-Of-Age 2.0
If you would like to read more about What Comes Next: https://amzn.to/4qJjRDj
What I Liked About What Comes Next:
A Weighted Decision:
If you have ever been faced with the decision of whether to have a genetics test performed, you will be able to relate to this story. Believe me, it isn’t an easy decision, and the outcome can change the rest of your life.
When Alex, in her twenties, finds out that her estranged mother died from Huntington’s disease, she and her sister, Meredith, must make the decision as to whether to be tested for it or not. Huntington’s disease causes the nerves in your brain cells to decay leading to severe disability and then fatality. Would you want to know if you inherited this disease? Alex and her sister make a pact to wait three months until they make this decision.
Sister’s Edition:
Since I have two sisters, I love reading about sibling relationships. I like how the characters of Alex and Meredith are polar opposites. Yet, they couldn’t be closer. Forbes does a wonderful job of showing how their relationship works through the trying times.
Romance and the Four-Legged Star:
I enjoyed the romance part of the story when Alex reconnects with an old flame named Nathan. With this story line, Nathan’s beautiful dog needs training. Guess who used to own a dog-training business? I loved reading about how Alex tries to train the dog to help the pup from being euthanized after biting another person. I actually learned a lot from her training techniques.
Although this book deals with some heavy issues, it is also a story of hope. Forbes shows that life can be messy in your twenties, but there is always light within that time. This would make a great book for your next book club.
My Favorite Quotes From What Comes Next:
“You let me be every version of myself, even the parts that I struggle to like. You show me that it’s okay to be every version. And I believe in us, even when you can’t.”
My Take: You know you have found your “person” when you can be every version of yourself. You need to find someone who believes in you, even when it is your messiest self.
“Being at risk never gets easy. It’s never okay. But one day, you wake up, and it’s just part of your life. You breathe in and out, and the risk is there, and that is simply (and not so simply) your life. And maybe you’ll live differently and maybe you won’t, and either way, that’s cool. That’s up to you. It’s your life. You get to choose. Just like anybody else.”
My Take: When you learn you are at risk of a genetic disease, you almost become a hypochondriac. Anything that happens to your body, you assume it’s your body telling you that “it’s time.” But then you need to tell yourself, it’s up to you how you are going to react. Forbes beautifully illustrates that while we can’t always choose our DNA, we can choose how we live with it.
Where To Buy This Book and More:
- Purchase What Comes Next by Caitlin Forbes: https://amzn.to/4aM4562
- Read more of my book reviews: https://judiholst.com/book-reviews/
- Missed my Top Books of 2024? Find them here: https://judiholst.com/top-20-books-that-i-loved-in-2024/
If you liked this book and also enjoy reading about sister bonds, then I would recommend:
- An Academic Affair by Jodi MacAlister
- The Sister Switch by Charlotte Butterfield
- Little Souls by Sandra Dallas
Thank you to NetGalley, Lake Union Publishing, and Caitlin Forbes for my free copy. This is my honest opinion.
To read more about Caitlin Forbes: https://caitlinforbes.mykajabi.com/
Leave a Comment:
If you were in Alex and Meredith’s shoes, would you choose to take the genetic test right away, or would you prefer to live in the dark for a while? I’d love to hear your perspective in the comments!


















